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transformi

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The answer TRANSFORMI has 0 possible clue(s) in existing crosswords.

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There are 10 letters in TRANSFORMI ( A¹F⁴I¹M³N¹O¹R¹S¹T¹ )

To search all scrabble anagrams of TRANSFORMI, to go: TRANSFORMI?

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6 letters out of TRANSFORMI

5 letters out of TRANSFORMI

AFRIT AIRNS AIRTS AMINO AMINS AMIRS AMNIO AMORT ANTIS ARMOR ARRIS ARSON ASTIR ATOMS FAINT FAIRS FANOS FARMS FAROS FARTS FATSO FIARS FIATS FINOS FIRMS FIRNS FIRST FOAMS FOINS FOIST FONTS FORAM FORMS FORTS FRATS FRIAR FRITS FRONS FRONT FROST INARM INFOS INFRA INTRO IOTAS IRONS MAINS MAIRS MAIST MANOR MANOS MARTS MASON MATIN MINAS MINOR MINTS MOANS MOATS MOIRA MOIST MONAS MORAS MORNS MORTS MOTIF NAIFS NARIS NITRO NOIRS NOMAS NORIA NORIS NORMS OMITS ORNIS ORRIS OSTIA RAFTS RAINS RANIS RANTS RATIO RATOS RIANT RIFTS RIOTS ROAMS ROANS ROARS ROAST ROMAN ROSIN ROTAS ROTIS SAINT SANTO SARIN SATIN SIMAR SIRRA SITAR SMART SNARF SNORT SOFAR SOFTA SOMAN SONAR SORTA STAIN STAIR STOAI STOMA STORM STRIA TAINS TAMIS TARNS TAROS TARSI TIROS TOMAN TORAS TORRS TORSI TRAIN TRAMS TRANS TRIMS TRIOS TROIS TRONA

4 letters out of TRANSFORMI

AIMS AINS AIRN AIRS AIRT AITS AMIN AMIR AMIS ANIS ANTI ANTS ARFS ARMS ARTS ATOM FAIN FAIR FANO FANS FARM FARO FART FAST FATS FIAR FIAT FINO FINS FIRM FIRN FIRS FIST FITS FOAM FOIN FONS FONT FORA FORM FORT FRAT FRIT FROM INFO INRO INTO IONS IOTA IRON MAIN MAIR MANO MANS MARS MART MAST MATS MINA MINT MIRS MISO MIST MOAN MOAS MOAT MONS MORA MORN MORS MORT MOST MOTS NAIF NAOI NAOS NIMS NITS NOIR NOMA NOMS NORI NORM NOTA OAFS OARS OAST OATS OMIT ORRA ORTS OSAR RAFT RAIN RAIS RAMI RAMS RANI RANT RATO RATS RIAS RIFS RIFT RIMS RINS RIOT ROAM ROAN ROAR ROMS ROTA ROTI ROTS SAIN SARI SATI SIFT SIMA SMIT SNIT SNOT SOAR SOFA SOFT SOMA SORA SORI SORN SORT STAR STIR STOA TAIN TAMS TANS TAOS TARN TARO TARS TINS TIRO TOMS TONS TORA TORI TORN TORR TORS TRAM TRIM TRIO TSAR

3 letters out of TRANSFORMI

AFT AIM AIN AIR AIS AIT AMI ANI ANT ARF ARM ARS ART FAN FAR FAS FAT FIN FIR FIT FON FOR FRO IFS INS ION ISM ITS MAN MAR MAS MAT MIR MIS MOA MON MOR MOS MOT NAM NIM NIT NOM NOR NOS NOT OAF OAR OAT OFT OMS ONS ORA ORS ORT RAI RAM RAN RAS RAT RIA RIF RIM RIN ROM ROT SAT SIM SIN SIR SIT SOM SON SOT SRI TAM TAN TAO TAR TAS TIN TIS TOM TON TOR

2 letters out of TRANSFORMI

AI AM AN AR AS AT FA IF IN IS IT MA MI MO NA NO OF OI OM ON OR OS SI SO TA TI TO

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Definitions of transformi in various dictionaries:

TRANSFORMI - Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes three di...

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Transformi might refer to
Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes three different mammalian isoforms (TGF-β 1 to 3, HGNC symbols TGFB1, TGFB2, TGFB3) and many other signaling proteins produced by all white blood cell lineages. A fourth member, TGFB4, has been identified in birds and a fifth, TGFB5, only in frogs. Activated TGF-β complexes with other factors to form a serine/threonine kinase complex that binds to TGF-β receptors, which is composed of both type 1 and type 2 receptor subunits. After the binding of TGF-β, the type 2 receptor kinase phosphorylates and activates the type 1 receptor kinase that activates a signaling cascade. This leads to the activation of different downstream substrates and regulatory proteins, inducing transcription of different target genes that function in differentiation, chemotaxis, proliferation, and activation of many immune cells.TGF-β is secreted by many cell types, including macrophages, in a latent form in which it is complexed with two other polypeptides, latent TGF-beta binding protein (LTBP) and latency-associated peptide (LAP). Serum proteinases such as plasmin catalyze the release of active TGF-β from the complex. This often occurs on the surface of macrophages where the latent TGF-β complex is bound to CD36 via its ligand, thrombospondin-1 (TSP-1). Inflammatory stimuli that activate macrophages enhance the release of active TGF-β by promoting the activation of plasmin. Macrophages can also endocytose IgG-bound latent TGF-β complexes that are secreted by plasma cells and then release active TGF-β into the extracellular fluid. Among its key functions is regulation of inflammatory processes, particularly in the gut. TGF-β also plays a crucial role in stem cell differentiation as well as T-cell regulation and differentiation. As such, it is a highly researched cytokine in the fields of cancer, auto-immune diseases, and infectious disease. * The TGF-β superfamily includes endogenous growth inhibiting proteins; an increase in expression of TGF-β often correlates with the malignancy of many cancers and a defect in the cellular growth inhibition response to TGF-β. Its immunosuppressive functions then come to dominate, contributing to oncogenesis. The disregulation of its immunosuppressive functions is also implicated in the pathogenesis of autoimmune diseases, although their effect is mediated by the environment of other cytokines present.

Transformi might refer to

Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes three different mammalian isoforms (TGF-β 1 to 3, HGNC symbols TGFB1, TGFB2, TGFB3) and many other signaling proteins produced by all white blood cell lineages. A fourth member, TGFB4, has been identified in birds and a fifth, TGFB5, only in frogs. Activated TGF-β complexes with other factors to form a serine/threonine kinase complex that binds to TGF-β receptors, which is composed of both type 1 and type 2 receptor subunits. After the binding of TGF-β, the type 2 receptor kinase phosphorylates and activates the type 1 receptor kinase that activates a signaling cascade. This leads to the activation of different downstream substrates and regulatory proteins, inducing transcription of different target genes that function in differentiation, chemotaxis, proliferation, and activation of many immune cells.TGF-β is secreted by many cell types, including macrophages, in a latent form in which it is complexed with two other polypeptides, latent TGF-beta binding protein (LTBP) and latency-associated peptide (LAP). Serum proteinases such as plasmin catalyze the release of active TGF-β from the complex. This often occurs on the surface of macrophages where the latent TGF-β complex is bound to CD36 via its ligand, thrombospondin-1 (TSP-1). Inflammatory stimuli that activate macrophages enhance the release of active TGF-β by promoting the activation of plasmin. Macrophages can also endocytose IgG-bound latent TGF-β complexes that are secreted by plasma cells and then release active TGF-β into the extracellular fluid. Among its key functions is regulation of inflammatory processes, particularly in the gut. TGF-β also plays a crucial role in stem cell differentiation as well as T-cell regulation and differentiation. As such, it is a highly researched cytokine in the fields of cancer, auto-immune diseases, and infectious disease.
* The TGF-β superfamily includes endogenous growth inhibiting proteins; an increase in expression of TGF-β often correlates with the malignancy of many cancers and a defect in the cellular growth inhibition response to TGF-β. Its immunosuppressive functions then come to dominate, contributing to oncogenesis. The disregulation of its immunosuppressive functions is also implicated in the pathogenesis of autoimmune diseases, although their effect is mediated by the environment of other cytokines present.

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