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hyperekplexia
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There are 13 letters in HYPEREKPLEXIA ( A1E1H4I1K5L1P3R1X8Y4 )
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Definitions of hyperekplexia in various dictionaries:
HYPEREKPLEXIA - Hyperekplexia ("exaggerated surprise") is a neurologic disorder classically characterised by pro noun ced startle responses to tactile or acoustic stim...
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| Hyperekplexia description |
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| Hyperekplexia ("exaggerated surprise") is a neurologic disorder classically characterised by pronounced startle responses to tactile or acoustic stimuli and hypertonia. The hypertonia may be predominantly truncal, attenuated during sleep and less prominent after a year of age. Classic hyperekplexia is caused by genetic mutations in a number of different genes, all of which play an important role in glycine neurotransmission. Glycine is used by the central nervous system as an inhibitory neurotransmitter. Hyperekplexia is generally classified as a genetic disease, but some disorders can mimic the exaggerated startle of hyperekplexia. |