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infliximab

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The answer INFLIXIMAB has 0 possible clue(s) in existing crosswords.

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The word INFLIXIMAB is NOT valid in any word game. (Sorry, you cannot play INFLIXIMAB in Scrabble, Words With Friends etc)

There are 10 letters in INFLIXIMAB ( A¹B³F⁴I¹L¹M³N¹X⁸ )

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4 letters out of INFLIXIMAB

3 letters out of INFLIXIMAB

AIL AIM AIN ALB AMI ANI BAL BAM BAN BIN FAB FAN FAX FIB FIL FIN FIX LAB LAM LAX LIB LIN MAN MAX MIB MIL MIX NAB NAM NIB NIL NIM NIX

2 letters out of INFLIXIMAB

AB AI AL AM AN AX BA BI FA IF IN LA LI MA MI NA XI

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Definitions of infliximab in various dictionaries:

noun - a monoclonal antibody (trade name Remicade) used to treat Crohn's disease and rheumatoid arthritis

noun - an anti-TNF compound (trade name Remicade) consisting of an antibody directed against TNF

INFLIXIMAB - Infliximab (trade names Remicade among others) is a chimeric monoclonal antibody biologic drug that works against tumor necrosis factor alpha (TNF-α...

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Infliximab description
Infliximab (trade names Remicade among others) is a chimeric monoclonal antibody biologic drug that works against tumor necrosis factor alpha (TNF-α) and is used to treat autoimmune diseases. Infliximab was approved by the U.S. Food and Drug Administration (FDA) for the treatment of Crohn's disease, ulcerative colitis, psoriasis, psoriatic arthritis, ankylosing spondylitis, and rheumatoid arthritis. It is used off-label outside its FDA approval for Behçet's disease and other conditions. Infliximab is administered by intravenous infusion, typically at six- to eight-week intervals. It cannot be given by mouth because the digestive system would destroy the drug.Infliximab works by binding to TNF-α. TNF-α is a chemical messenger (cytokine) and a key part of the autoimmune reaction. In rheumatoid arthritis, infliximab seems to work by preventing TNF-α from binding to its receptor in the cell. * Infliximab is an artificial antibody. It was originally developed in mice as a mouse antibody. Because humans have immune reactions to mouse proteins, the mouse common domains were replaced with similar human antibody domains. They are monoclonal antibodies and have identical structures and affinities to the target. Because they are a combination of mouse and human antibody amino acid sequences, they are called a "chimeric monoclonal antibody". In the United States, Remicade can cost as much as $19,000 per month.Infliximab biosimilars have been approved in the EU (2013), Japan (2014), and USA (2016).

Infliximab description

Infliximab (trade names Remicade among others) is a chimeric monoclonal antibody biologic drug that works against tumor necrosis factor alpha (TNF-α) and is used to treat autoimmune diseases. Infliximab was approved by the U.S. Food and Drug Administration (FDA) for the treatment of Crohn's disease, ulcerative colitis, psoriasis, psoriatic arthritis, ankylosing spondylitis, and rheumatoid arthritis. It is used off-label outside its FDA approval for Behçet's disease and other conditions. Infliximab is administered by intravenous infusion, typically at six- to eight-week intervals. It cannot be given by mouth because the digestive system would destroy the drug.Infliximab works by binding to TNF-α. TNF-α is a chemical messenger (cytokine) and a key part of the autoimmune reaction. In rheumatoid arthritis, infliximab seems to work by preventing TNF-α from binding to its receptor in the cell.
* Infliximab is an artificial antibody. It was originally developed in mice as a mouse antibody. Because humans have immune reactions to mouse proteins, the mouse common domains were replaced with similar human antibody domains. They are monoclonal antibodies and have identical structures and affinities to the target. Because they are a combination of mouse and human antibody amino acid sequences, they are called a "chimeric monoclonal antibody". In the United States, Remicade can cost as much as $19,000 per month.Infliximab biosimilars have been approved in the EU (2013), Japan (2014), and USA (2016).

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