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genot
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The answer GENOT has 0 possible clue(s) in existing crosswords.
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The word GENOT is NOT valid in any word game. (Sorry, you cannot play GENOT in Scrabble, Words With Friends etc)
There are 5 letters in GENOT ( E1G2N1O1T1 )
To search all scrabble anagrams of GENOT, to go: GENOT?
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Definitions of genot in various dictionaries:
GENOT - In genetics, genotoxicity describes the property of chemical agents that damages the genetic information within a cell causing mutations, which may l...
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Genot might refer to |
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In genetics, Genotoxicity describes the property of chemical agents that damages the genetic information within a cell causing mutations, which may lead to cancer. While genotoxicity is often confused with mutagenicity, all mutagens are genotoxic, whereas not all genotoxic substances are mutagenic. The alteration can have direct or indirect effects on the DNA: the induction of mutations, mistimed event activation, and direct DNA damage leading to mutations. The permanent, heritable changes can affect either somatic cells of the organism or germ cells to be passed on to future generations. Cells prevent expression of the genotoxic mutation by either DNA repair or apoptosis; however, the damage may not always be fixed leading to mutagenesis. * To assay for genotoxic molecules, researchers assay for DNA damage in cells exposed to the toxic substrates. This DNA damage can be in the form of single- and double-strand breaks, loss of excision repair, cross-linking, alkali-labile sites, point mutations, and structural and numerical chromosomal aberrations. The compromised integrity of the genetic material has been known to cause cancer. As a consequence, many sophisticated techniques including Ames Assay, in vitro and in vivo Toxicology Tests, and Comet Assay have been developed to assess the chemicals' potential to cause DNA damage that may lead to cancer. |