Welcome to Anagrammer Crossword Genius! Keep reading below to see if tki is an answer to any crossword puzzle or word game (Scrabble, Words With Friends etc). Scroll down to see all the info we have compiled on tki.
tki
Searching in Crosswords ...
The answer TKI has 0 possible clue(s) in existing crosswords.
Searching in Word Games ...
The word TKI is NOT valid in any word game. (Sorry, you cannot play TKI in Scrabble, Words With Friends etc)
There are 3 letters in TKI ( I1K5T1 )
To search all scrabble anagrams of TKI, to go: TKI?
Rearrange the letters in TKI and see some winning combinations
Scrabble results that can be created with an extra letter added to TKI
3 letters out of TKI
Searching in Dictionaries ...
Definitions of tki in various dictionaries:
TKI - A tyrosine kinase inhibitor (TKI) is a pharmaceutical drug that inhibits tyrosine kinases. Tyrosine kinases are enzymes responsible for the activatio...
Word Research / Anagrams and more ...
Keep reading for additional results and analysis below.
| Tki might refer to |
|---|
|
A tyrosine kinase inhibitor (TKI) is a pharmaceutical drug that inhibits tyrosine kinases. Tyrosine kinases are enzymes responsible for the activation of many proteins by signal transduction cascades. The proteins are activated by adding a phosphate group to the protein (phosphorylation), a step that TKIs inhibit. TKIs are typically used as anticancer drugs. For example, they have substantially improved outcomes in chronic myelogenous leukemia. * They are also called tyrphostins, the short name for “tyrosine phosphorylation inhibitor”, originally coined in a 1988 publication, which was the first description of compounds inhibiting the catalytic activity of the epidermal growth factor receptor (EGFR). * The 1988 study was the first demonstration of a systematic search and discovery of small-molecular-weight inhibitors of tyrosine phosphorylation, which do not inhibit protein kinases that phosphorylate serine or threonine residues and can discriminate between the kinase domains of the EGFR and that of the insulin receptor. It was further shown that in spite of the conservation of the tyrosine-kinase domains one can design and synthesize tyrphostins that discriminate between even closely related protein tyrosine kinases such as EGFR and its close relative HER2. |