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specializes
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The answer SPECIALIZES has 2 possible clue(s) in existing crosswords.
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The word SPECIALIZES is VALID in some board games. Check SPECIALIZES in word games in Scrabble, Words With Friends, see scores, anagrams etc.
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Definitions of specializes in various dictionaries:
verb - become more focus on an area of activity or field of study
verb - be specific about
verb - suit to a special purpose
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Possible Crossword Clues |
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focuses on one thing |
Last Seen in these Crosswords & Puzzles |
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Oct 24 2015 7 Little Words Daily Puzzle |
Oct 24 2015 7 Little Words Daily Puzzle |
Specializes might refer to |
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Specialized pro-resolving mediators (SPM, also termed specialized proresolving mediators) are a large and growing class of cell signaling molecules formed in cells by the metabolism of polyunsaturated fatty acids (PUFA) by one or a combination of lipoxygenase, cyclooxygenase, and cytochrome P450 monooxygenase enzymes. Pre-clinical studies, primarily in animal models and human tissues, implicate SPM in orchestrating the resolution of inflammation.SPM join the long list of other physiological agents which tend to limit inflammation (see Inflammation § Resolution of inflammation) including glucocorticoids, interleukin 10 (an anti-inflammatory cytokine), interleukin 1 receptor antagonist (an inhibitor of the action of pro-inflammatory cytokine, interleukin 1), annexin A1 (an inhibitor of formation of pro-inflammatory metabolites of polyunsaturated fatty acids), and the gaseous resolvins, carbon monoxide (see Carbon monoxide § Normal human physiology), nitric oxide (see Nitric oxide § Biological functions), and hydrogen sulfide (see Hydrogen sulfide § Function in the body and Hydrogen sulfide § Involvement in diseases).The absolute as well as relative roles of the SPM along with other physiological anti-inflammatory agents in resolving human inflammatory responses remain to be defined precisely. However, studies suggest that synthetic SPM that are resistant to being metabolically inactivated hold promise of being clinically useful pharmacological tools for preventing and resolving a wide range of pathological inflammatory responses along with the tissue destruction and morbidity that these responses cause. Based on animal model studies, the inflammation-based diseases which may be treated by such metabolically resistant SPM analogs include not only pathological and tissue damaging responses to invading pathogens but also a wide array of pathological conditions in which inflammation is a contributing factor such as allergic inflammatory diseases (e.g. asthma, rhinitis), autoimmune diseases ( e.g. rheumatoid arthritis, systemic lupus erythematosus), psoriasis, atherosclerosis disease leading to heart attacks and strokes, type 1 and type 2 diabetes, the metabolic syndrome, and certain dementia syndromes (e.g. Alzheimer's disease, Huntington's disease).Many of the SPM are metabolites of omega-3 fatty acids and have been proposed to be responsible for the anti-inflammatory actions that are attributed to omega-3 fatty acid-rich diets. |