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sialagogue
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Definitions of sialagogue in various dictionaries:
A drug or other agent that increases the flow of saliva.
SIALAGOGUE - A sialogogue, sialagogue, ptysmagogue or ptyalagogue is a drug or substance that increases the flow rate of saliva.Sialogogues can be used in the tre...
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A sialogogue, sialagogue, ptysmagogue or ptyalagogue is a drug or substance that increases the flow rate of saliva.Sialogogues can be used in the treatment of xerostomia (the subjective feeling of having a dry mouth), to stimulate any functioning salivary gland tissue to produce more saliva. Saliva has a bactericidal effect, so when low levels of it are secreted, the risk of caries increases. Not only this, but fungal infections such as oral candidosis also can be a consequence of low salivary flow rates. The buffer effect of saliva is also important, neutralising acids that cause tooth enamel demineralisation. The following are used in dentistry to treat xerostomia: * Parasympathomimetic drugs act on parasympathetic muscarinic receptors to induce an increased saliva flow. The M3 receptor has been identified as the principal target to increase salivary flow rates. Pilocarpine is an example; the maximum dose of this drug is 30 mg/day. Contraindications include many lung conditions, such a |