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penicillinases
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The answer PENICILLINASES has 0 possible clue(s) in existing crosswords.
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Definitions of penicillinases in various dictionaries:
noun - enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic
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| Plural form of penicillinase. |
| Penicillinases might refer to |
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| Beta-lactamases are enzymes (EC 3.5.2.6) produced by bacteria that provide multi-resistance to β-lactam antibiotics such as penicillins, cephalosporins, cephamycins, and carbapenems (ertapenem), although carbapenems are relatively resistant to beta-lactamase. Beta-lactamase provides antibiotic resistance by breaking the antibiotics' structure. These antibiotics all have a common element in their molecular structure: a four-atom ring known as a β-lactam. Through hydrolysis, the lactamase enzyme breaks the β-lactam ring open, deactivating the molecule's antibacterial properties. * Beta-lactam antibiotics are typically used to treat a broad spectrum of Gram-positive and Gram-negative bacteria. * Beta-lactamases produced by Gram-negative organisms are usually secreted, especially when antibiotics are present in the environment. |