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penicillinase
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The answer PENICILLINASE has 0 possible clue(s) in existing crosswords.
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Definitions of penicillinase in various dictionaries:
noun - enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic
Any of various enzymes, produced by certain bacteria, that hydrolyze penicillin and are used in medicine to treat allergic reactions to penicillin.
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| Possible Dictionary Clues |
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| Any of various enzymes that are produced by certain bacteria, including most strains of staphylococci, and that hydrolyze and inactivate penicillin. They are used in medicine to treat allergic reactions to penicillin. Also called beta-lactamase. |
| enzyme produced by certain bacteria that inactivates penicillin and results in resistance to that antibiotic |
| Penicillinase might refer to |
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| Beta-lactamases are enzymes (EC 3.5.2.6) produced by bacteria that provide multi-resistance to β-lactam antibiotics such as penicillins, cephalosporins, cephamycins, and carbapenems (ertapenem), although carbapenems are relatively resistant to beta-lactamase. Beta-lactamase provides antibiotic resistance by breaking the antibiotics' structure. These antibiotics all have a common element in their molecular structure: a four-atom ring known as a β-lactam. Through hydrolysis, the lactamase enzyme breaks the β-lactam ring open, deactivating the molecule's antibacterial properties. * Beta-lactam antibiotics are typically used to treat a broad spectrum of Gram-positive and Gram-negative bacteria. * Beta-lactamases produced by Gram-negative organisms are usually secreted, especially when antibiotics are present in the environment. |