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paclitaxel
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Definitions of paclitaxel in various dictionaries:
PACLITAXEL - Paclitaxel (PTX), sold under the brand name Taxol among others, is a chemotherapy medication used to treat a number of types of cancer. This includes...
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| An anticancer drug derived from the bark of the Pacific yew tree and used in the treatment of ovarian and breast cancer that has not responded to prior therapy. |
| A taxane originally isolated from the bark of the Pacific yew, Taxus brevifolia, which interferes with microtubule function and inhibits cell division, and is used in the treatment of some cancers, especially those of the breast and ovary. A trademark for this drug is Taxol. |
| Paclitaxel description |
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| Paclitaxel (PTX), sold under the brand name Taxol among others, is a chemotherapy medication used to treat a number of types of cancer. This includes ovarian cancer, breast cancer, lung cancer, Kaposi sarcoma, cervical cancer, and pancreatic cancer. It is given by injection into a vein. There is also an albumin bound formulation.Common side effects include hair loss, bone marrow suppression, numbness, allergic reactions, muscle pains, and diarrhea. Other serious side effects include heart problems, increased risk of infection, and lung inflammation. There are concerns that use during pregnancy may cause birth defects. Paclitaxel is in the taxane family of medications. It works by interference with the normal function of microtubules during cell division.Paclitaxel was first isolated in 1971 from the Pacific yew and approved for medical use in 1993. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about 7.06 to 13.48 USD per 100 mg vial. This amount in the United Kingdom costs the NHS about 66.85 pounds. It is now manufactured by cell culture. |