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nalbuphine
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The answer NALBUPHINE has 0 possible clue(s) in existing crosswords.
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Definitions of nalbuphine in various dictionaries:
NALBUPHINE - Nalbuphine, sold under the brand names Nubain and Nalpain among others, is a opioid analgesic which is used in the treatment of pain. It is given by ...
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| A synthetic opioid used commercially as an analgesic. |
| Nalbuphine description |
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| Nalbuphine, sold under the brand names Nubain and Nalpain among others, is a opioid analgesic which is used in the treatment of pain. It is given by injection into a vein, muscle, or fat.Side effects of nalbuphine include sedation, sweatiness, clamminess, nausea, vomiting, dizziness, vertigo, dry mouth, and headache. Unlike other opioids, it has little to no capacity for euphoria or respiratory depression. It also has little to no incidence of dysphoria, dissociation, hallucinations, and related side effects at typical therapeutic doses. Nalbuphine is a mixed agonist/antagonist opioid modulator. Specifically, it acts as a moderate-efficacy partial agonist agonist or antagonist of the -opioid receptor (MOR) and as a high-efficacy partial agonist of the -opioid receptor (KOR), whereas it has relatively low affinity for the -opioid receptor (DOR) and sigma receptors.Nalbuphine was discovered in 1965 and was introduced for medical use in the United States in 1979. It is marketed in many co |