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ESTOONE
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The answer ESTOONE has 0 possible clue(s) in existing crosswords.
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Definitions of estoone in various dictionaries:
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| Estoone might refer to |
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| Estrone, sold under the brand names Estragyn, Kestrin, and Theelin among many others, is an estrogen medication and naturally occurring steroid hormone which has been used in menopausal hormone therapy and for other indications. It has been available as an aqueous suspension or oil solution that is given by injection into muscle and as a vaginal cream that is applied inside of the vagina. It can also be taken by mouth in the form of estrone sulfate, as in estropipate (piperazine estrone sulfate; Ogen) and conjugated estrogens (Premarin).Side effects of estrogens like estrone include breast tenderness, breast enlargement, headache, nausea, fluid retention, and edema, among others. Estrone is a naturally occurring and bioidentical estrogen, or an agonist of the estrogen receptor, the biological target of estrogens like endogenous estradiol. It is a relatively weak estrogen, with much lower activity than estradiol. However, estrone is converted in the body into estradiol, which provides most of its estrogenic potency. As such, estrone can be considered to be a prodrug of estradiol.Estrone was first discovered in 1929, and was introduced for medical use shortly thereafter. Although it has been used clinically in the past, estrone has largely been discontinued and is mostly no longer marketed. |
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