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corticotropin
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Definitions of corticotropin in various dictionaries:
noun - a hormone produced by the anterior pituitary gland that stimulates the adrenal cortex
See ACTH.
CORTICOTROPIN - Adrenocorticotropic hormone (ACTH, also adrenocorticotropin, corticotropin) is a polypeptide tropic hormone produced by and secreted by the anterior ...
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| See ACTH. |
| a hormone produced by the anterior pituitary gland that stimulates the adrenal cortex |
| Corticotropin description |
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Adrenocorticotropic hormone (ACTH, also adrenocorticotropin, corticotropin) is a polypeptide tropic hormone produced by and secreted by the anterior pituitary gland. It is also used as a medication and diagnostic agent. * ACTH is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress (along with its precursor corticotropin-releasing hormone from the hypothalamus). Its principal effects are increased production and release of cortisol by the cortex of the adrenal gland. ACTH is also related to the circadian rhythm in many organisms.Deficiency of ACTH is a sign of secondary adrenal insufficiency (suppressed production of ACTH due to an impairment of the pituitary gland or hypothalamus, cf. hypopituitarism) or tertiary adrenal insufficiency (disease of the hypothalamus, with a decrease in the release of corticotropin releasing hormone CRH). Conversely, chronically elevated ACTH levels occur in primary adrenal insufficiency (e |