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ceoperas
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The answer CEOPERAS has 1 possible clue(s) in existing crosswords.
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The word CEOPERAS is NOT valid in any word game. (Sorry, you cannot play CEOPERAS in Scrabble, Words With Friends etc)
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Definitions of ceoperas in various dictionaries:
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Last Seen in these Crosswords & Puzzles |
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Aug 4 2011 New York Times |
Ceoperas might refer to |
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Cloperastine (INN) or cloperastin, also known as cloperastine hydrochloride (JAN) (brand names Hustazol, Nitossil, Seki) and cloperastine fendizoate (or hybenzoate), is an antitussive and antihistamine that is marketed as a cough suppressant in Japan, Hong Kong, and in some European countries. It was first introduced in 1972 in Japan, and then in Italy in 1981. The precise mechanism of action of cloperastine is not fully clear, but several different biological activities have been identified for the drug, of which include: ligand of the σ1 receptor (Ki = 20 nM) (likely an agonist), GIRK channel blocker (described as "potent"), antihistamine (Ki = 3.8 nM for the H1 receptor), and anticholinergic. It is thought that the latter two properties contribute to side effects, such as sedation and somnolence, while the former two may be involved in or responsible for the antitussive efficacy of cloperastine. |