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CROSSWORD
ANSWER

thecape

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The answer THECAPE has 6 possible clue(s) in existing crosswords.

Searching in Word Games ...

The word THECAPE is NOT valid in any word game. (Sorry, you cannot play THECAPE in Scrabble, Words With Friends etc)

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Definitions of thecape in various dictionaries:

No definitions found

Word Research / Anagrams and more ...

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Possible Crossword Clues
New England vacation spot, popularly
Massachusetts peninsula, to residents
Where there's some hope for those that are good, perhaps
Martha's Vineyard alternative
Cheat badly with first couple of penalties in part of SA
New England vacation destination, familiarly

Last Seen in these Crosswords & Puzzles
Jun 25 2023 New York Times
Aug 2 2016 New York Times
Oct 31 2010 The Washington Post
Jul 11 2010 The Telegraph - Cryptic
May 4 2006 L.A. Times Daily
May 11 1999 Irish Times (Crosaire)

Thecape might refer to
The therapeutic index (TI; also referred to as therapeutic ratio) is a comparison of the amount of a therapeutic agent that causes the therapeutic effect to the amount that causes toxicity. The related terms therapeutic window or safety window refer to a range of doses which optimize between efficacy and toxicity, achieving the greatest therapeutic benefit without resulting in unacceptable side-effects or toxicity. * Classically, in an established clinical indication setting of an approved drug, TI refers to the ratio of the dose of drug that causes adverse effects at an incidence/severity not compatible with the targeted indication (e.g. toxic dose in 50% of subjects, TD50) to the dose that leads to the desired pharmacological effect (e.g. efficacious dose in 50% of subjects, ED50). In contrast, in a drug development setting TI is calculated based on plasma exposure levels.In the early days of pharmaceutical toxicology, TI was frequently determined in animals as lethal dose of a drug for 50% of the population (LD50) divided by the minimum effective dose for 50% of the population (ED50). Today, more sophisticated toxicity endpoints are used.* * * * * * Therapeutic * * Index * * * * = * * * * * * LD * * 50 * * * * * * * ED * * 50 * * * * * * * * * * * {\displaystyle {\ce {{Therapeutic\ Index}\ =\ {\frac {LD50}{ED50}}}}} * in animal studies, or for humans, * * * * * * Therapeutic * * Index * * * * = * * * * * * TD * * 50 * * * * * * * ED * * 50 * * * * * * * * * * * {\displaystyle {\ce {{Therapeutic\ Index}\ =\ {\frac {TD50}{ED50}}}}} * For many drugs, there are severe toxicities that occur at sublethal doses in humans, and these toxicities often limit the maximum dose of a drug. A higher therapeutic index is preferable to a lower one: a patient would have to take a much higher dose of such a drug to reach the toxic threshold than the dose taken to elicit the therapeutic effect. * Generally, a drug or other therapeutic agent with a narrow therapeutic range (i.e. having little difference between toxic and therapeutic doses) may have its dosage adjusted according to measurements o...

Thecape might refer to

The therapeutic index (TI; also referred to as therapeutic ratio) is a comparison of the amount of a therapeutic agent that causes the therapeutic effect to the amount that causes toxicity. The related terms therapeutic window or safety window refer to a range of doses which optimize between efficacy and toxicity, achieving the greatest therapeutic benefit without resulting in unacceptable side-effects or toxicity.
* Classically, in an established clinical indication setting of an approved drug, TI refers to the ratio of the dose of drug that causes adverse effects at an incidence/severity not compatible with the targeted indication (e.g. toxic dose in 50% of subjects, TD50) to the dose that leads to the desired pharmacological effect (e.g. efficacious dose in 50% of subjects, ED50). In contrast, in a drug development setting TI is calculated based on plasma exposure levels.In the early days of pharmaceutical toxicology, TI was frequently determined in animals as lethal dose of a drug for 50% of the population (LD50) divided by the minimum effective dose for 50% of the population (ED50). Today, more sophisticated toxicity endpoints are used.*
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* {\displaystyle {\ce {{Therapeutic\ Index}\ =\ {\frac {LD50}{ED50}}}}}
* in animal studies, or for humans,
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* {\displaystyle {\ce {{Therapeutic\ Index}\ =\ {\frac {TD50}{ED50}}}}}
* For many drugs, there are severe toxicities that occur at sublethal doses in humans, and these toxicities often limit the maximum dose of a drug. A higher therapeutic index is preferable to a lower one: a patient would have to take a much higher dose of such a drug to reach the toxic threshold than the dose taken to elicit the therapeutic effect.
* Generally, a drug or other therapeutic agent with a narrow therapeutic range (i.e. having little difference between toxic and therapeutic doses) may have its dosage adjusted according to measurements o...

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