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polyribosome
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Definitions of polyribosome in various dictionaries:
A cluster of ribosomes connected by a strand of messenger RNA and functioning as a unit in protein synthesis.
POLYRIBOSOME - A polyribosome (or polysome) is a complex of an mRNA molecule and two or more ribosomes that act to translate mRNA instructions into polypeptides. Or...
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| A cluster of ribosomes connected by a strand of messenger RNA and actively synthesizing protein. Also called polysome. |
| Polyribosome description |
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| A polyribosome (or polysome) is a complex of an mRNA molecule and two or more ribosomes that act to translate mRNA instructions into polypeptides. Originally coined "ergosomes" in 1963, they were further characterized by Jonathan Warner, Paul M. Knopf, and Alex Rich. The simultaneous analysis of the polysome with all the peptides it produces under given conditions (the translatome) lead to a better insight of the complexity of how mutations, extracellular stimuli, intercellular cues, growth conditions, and stress could lead to the change of translation in the cell. Polysomes consist of varying numbers of ribosomes, and each ribosome contributes to the addition of its substantial mass. They act as a platform for signalling molecules to get involved in the emergence of polypeptides and ribosomes, and aid the nascent polypeptides to fold in the presence of chaperones, which later impact on the function of synthesized polysomes. |