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dioxi
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There are 5 letters in DIOXI ( D2I1O1X8 )
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Dioxins and dioxin-like compounds (DLCs) are compounds that are highly toxic environmental persistent organic pollutants (POPs). They are mostly by-products of various industrial processes - or, in case of dioxin-like PCBs and PBBs, part of intentionally produced mixtures. They include: * Polychlorinated dibenzo-p-dioxins (PCDDs), or simply dioxins. PCDDs are derivatives of dibenzo-p-dioxin. There are 75 PCDD congeners, differing in the number and location of chlorine atoms, and seven of them are especially toxic, the most dangerous being 2,3,7,8-Tetrachlorodibenzodioxin (TCDD) * Polychlorinated dibenzofurans (PCDFs), or furans. PCDFs are derivatives of dibenzofuran. There are 135 isomers, ten have dioxin-like properties. * Polychlorinated/polybrominated biphenyls (PCBs/PBBs), derived from biphenyl, of which twelve are "dioxin-like". Under certain conditions PCBs may form dibenzofurans/dioxins through partial oxidation. * Finally, dioxin may refer to 1,4-Dioxin proper, the basic chemical unit of the more complex dioxins. This simple compound is not persistent and has no PCDD-like toxicity. * * * * Because dioxins refer to such a broad class of compounds that vary widely in toxicity, the concept of toxic equivalency factor (TEF) has been developed to facilitate risk assessment and regulatory control. Toxic equivalence factors (TEFs) exist for seven congeners of dioxins, ten furans and twelve PCBs. The reference congener is the most toxic dioxin 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) which per definition has a TEF of one.In reference to their importance as environmental toxicants the term dioxins is used almost exclusively to refer to the sum of compounds (as TEQ) from the above groups which demonstrate the same specific toxic mode of action associated with TCDD. These include 17 PCDD/Fs and 12 PCBs. Incidents of contamination with PCBs are also often reported as dioxin contamination incidents since it is this toxic characteristic which is of most public and regulatory concern. |