Crossword Solver > found answer > SPEEDBALLING

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speedballing

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Speedballing might refer to
Speedball (or powerball) is a mix of cocaine with heroin or morphine taken intravenously or by insufflation. The original speedball used cocaine hydrochloride mixed with morphine sulfate, as opposed to heroin. Speedball may also use pharmaceutical opioids, benzodiazepines or barbiturates along with stimulants. However, since opioids and sedative-hypnotics have different objective and subjective effects, stimulant-depressant mixtures are known by the slang term "set up". A cocktail of drugs containing an opioid can cause a strong physical dependence and withdrawal symptoms. * These mixtures are often more potent than the sum of their parts, through drug synergy; this is an effect that can and has been used clinically, such as Brompton cocktail, the caffeine content of many codeine and dihydrocodeine combination drugs, and the use of stimulants both to potentiate the opioid and combat somnolence caused by high and rapidly escalating doses.*

Speedballing might refer to

Speedball (or powerball) is a mix of cocaine with heroin or morphine taken intravenously or by insufflation. The original speedball used cocaine hydrochloride mixed with morphine sulfate, as opposed to heroin. Speedball may also use pharmaceutical opioids, benzodiazepines or barbiturates along with stimulants. However, since opioids and sedative-hypnotics have different objective and subjective effects, stimulant-depressant mixtures are known by the slang term "set up". A cocktail of drugs containing an opioid can cause a strong physical dependence and withdrawal symptoms.
* These mixtures are often more potent than the sum of their parts, through drug synergy; this is an effect that can and has been used clinically, such as Brompton cocktail, the caffeine content of many codeine and dihydrocodeine combination drugs, and the use of stimulants both to potentiate the opioid and combat somnolence caused by high and rapidly escalating doses.*

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