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prodrugs
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Definitions of prodrugs in various dictionaries:
noun - an inactive chemical substance that becomes an active drug in the body
PRODRUGS - A prodrug is a medication or compound that, after administration, is metabolized (i.e., converted within the body) into a pharmacologically active dr...
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| Plural form of prodrug. |
| Prodrugs description |
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| A prodrug is a medication or compound that, after administration, is metabolized (i.e., converted within the body) into a pharmacologically active drug. Inactive prodrugs are pharmacologically inactive medications that are metabolized into an active form within the body. Instead of administering a drug directly, a corresponding prodrug might be used instead to improve how a medicine is absorbed, distributed, metabolized, and excreted (ADME). Prodrugs are often designed to improve bioavailability when a drug itself is poorly absorbed from the gastrointestinal tract. A prodrug may be used to improve how selectively the drug interacts with cells or processes that are not its intended target. This reduces adverse or unintended effects of a drug, especially important in treatments like chemotherapy, which can have severe unintended and undesirable side effects. |