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cholinesterase
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Definitions of cholinesterase in various dictionaries:
noun - an enzyme that hydrolyses acetylcholine (into choline and acetic acid)
An enzyme found chiefly at nerve terminals that inactivates acetylcholine by hydrolyzing it to form acetic acid and choline.
CHOLINESTERASE - In biochemistry, a cholinesterase or choline esterase is an esterase that lyses choline-based esters, several of which serve as neurotransmitters. Th...
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An enzyme found primarily at nerve endings that catalyzes the hydrolysis of acetylcholine into acetic acid and choline. |
an enzyme that hydrolyses acetylcholine (into choline and acetic acid) |
An enzyme, especially acetylcholinesterase, which hydrolyses esters of choline. |
Cholinesterase description |
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In biochemistry, a cholinesterase or choline esterase is an esterase that lyses choline-based esters, several of which serve as neurotransmitters. Thus, it is either of two enzymes that catalyze the hydrolysis of these cholinergic neurotransmitters, such as breaking acetylcholine into choline and acetic acid. These reactions are necessary to allow a cholinergic neuron to return to its resting state after activation. For example, in muscle contraction, acetylcholine at a neuromuscular junction triggers a contraction; but for the muscle to relax afterward, rather than remaining locked in a tense state, the acetylcholine must be broken down by a choline esterase. The main type for that purpose is acetylcholinesterase (also called choline esterase I or erythrocyte cholinesterase); it is found mainly in chemical synapses and red blood cell membranes. The other type is butyrylcholinesterase (also called choline esterase II or plasma cholinesterase); it is found mainly in the blood plasma. |