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urease
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Definitions of urease in various dictionaries:
noun - an enzyme that catalyzes the hydrolysis of urea into carbon dioxide and ammonia
An enzyme that promotes the hydrolysis of urea to form ammonium carbonate.
adj - a complex protein [n -S] : ENZYMIC
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Ureases (EC 3.5.1.5), functionally, belong to the superfamily of amidohydrolases and phosphotriesterases. Ureases are found in numerous bacteria, fungi, algae, plants, and some invertebrates, as well as in soils, as a soil enzyme. They are nickel-containing metalloenzymes of high molecular weight.These enzymes catalyze the hydrolysis of urea into carbon dioxide and ammonia:* (NH2)2CO + H2O CO2 + 2NH3The hydrolysis of urea occurs in two stages. In the first stage, ammonia and carbamate are produced. The carbamate spontaneously and rapidly hydrolyzes to ammonia and carbonic acid. Urease activity increase the pH of its environment as it produces ammonia, which is basic. * Its activity was first identified in 1876 by Frédéric Alphonse Musculus as a soluble ferment. * In 1926, James B. Sumner, showed that urease is a protein by examining its crystallized form. Sumner's work was the first demonstration that a protein can function as an enzyme and led eventually to the recognition that most en |