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ototoxic
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The answer OTOTOXIC has 0 possible clue(s) in existing crosswords.
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Definitions of ototoxic in various dictionaries:
adj - toxic to the organs of hearing or balance or to the auditory nerve
Having a toxic effect on the structures of the ear, especially on its nerve supply.
adj - adversely affecting hearing or balance
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| Possible Dictionary Clues |
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| Having a toxic effect on the structures of the ear, especially on its nerve supply. |
| toxic to the organs of hearing or balance or to the auditory nerve |
| Ototoxic description |
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Ototoxicity is the property of being toxic to the ear (oto-), specifically the cochlea or auditory nerve and sometimes the vestibular system, for example, as a side effect of a drug. The effects of ototoxicity can be reversible and temporary, or irreversible and permanent. * It has been recognized since the 19th century. * There are many well-known ototoxic drugs used in clinical situations, and they are prescribed, despite the risk of hearing disorders, to very serious health conditions. * Ototoxic drugs include antibiotics such as gentamicin, loop diuretics such as furosemide and platinum-based chemotherapy agents such as cisplatin. A number of nonsteroidal anti-inflammatory drugs (NSAIDS) have also been shown to be ototoxic. This can result in sensorineural hearing loss, dysequilibrium, or both. Some environmental and occupational chemicals have also been shown to affect the auditory system and interact with noise. |