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lysins
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Definitions of lysins in various dictionaries:
noun - any substance (such as an antibody) or agent that can cause lysis
noun - a substance capable of disintegrating blood cells or bacteria
LYSINS - Lysins, also known as endolysins or murein hydrolases, are hydrolytic enzymes produced by bacteriophages in order to cleave the host's cell wall duri...
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Possible Dictionary Clues |
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the disintegration of a cell by rupture of the cell wall or membrane. |
An antibody or other substance able to cause lysis of cells (especially bacteria). |
Lysins might refer to |
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Lysins, also known as endolysins or murein hydrolases, are hydrolytic enzymes produced by bacteriophages in order to cleave the host's cell wall during the final stage of the lytic cycle. Lysins are highly evolved enzymes that are able to target one of the five bonds in peptidoglycan (murein), the main component of bacterial cell walls, which allows the release of progeny virions from the lysed cell. Cell-wall-containing Archaea are also lysed by specialized pseudomurein-cleaving lysins, while most archaeal viruses employ alternate mechanisms. Similarly, not all bacteriophages synthesize lysins: some small single-stranded DNA and RNA phages produce membrane proteins that activate the host's autolytic mechanisms.Lysins are being used as antibacterial agents due to their high effectiveness and specificity in comparison with antibiotics, which are susceptible to bacterial resistance. |